Swanicoco EGF and FGF Pure Ampoule Review

Disclaimer: These items were provided to me at no cost by W2Beauty for review purposes. All opinions expressed are my own. This post does not contain affiliate links.

Product Names
Swanicoco Skin Expert Two Step EGF 10ppm Pure AmpouleSwanicoco Skin Expert Two Step FGF 10ppm Pure Ampoule

Country of Origin
South Korea

Where does it fit in your routine? / Usage Notes
This can be used in the serum step. I apply after watery essence and toner steps but before emulsions or creams.
The bottle of FGF ampoule lasted me for 4.5 weeks of daily usage. The EGF ampoule lasted me just under 6 weeks. Each bottle started out with the same amount of product and the dropper caps are identical, but I think the fact that the FGF ampoule is slightly more fluid made it easier to pick up more product with each use. Other than the first week of testing (which I used EGF on the right side of my face and FGF on the left), I used the ampoules by mixing them together in my palm and applying to my face in one go.

Size and Price
Each bottle contains 15ml of product and costs $73 on W2Beauty (EGF, FGF) and Koreadepart (EGF, FGF).

Both ampoules come in the same opaque, sturdy glass bottles with dropper caps. The EGF comes in a silver bottle and the FGF comes in gold. The dropper bottle works but does not reach all the way to the bottle of the bottle so towards the end I resorted to tipping the bottle over to pour the ampoule into my hand.

EGF ampoule on the left, FGF on the right.

Despite the inclusion of Rosa Damascena Flower Oil in the ingredients, I really don’t detect much if any fragrance.

Color and texture
Both ampoules are a watery gel in texture. The EGF ampoule is a little thicker and more white/cloudy in appearance whereas the FGF ampoule is a little thinner and clear in color.


  • EGF (EPIDERMAL GROWTH FACTOR): rh-Oligopeptide-1 
    EGF works by binding to a cell receptor and signaling growth and proliferation of new cells. Clinically, it is used to treat wounds but shows promise as a skincare ingredient.
    A 3 month study on 29 females aged 39 – 75 demonstrated that a twice daily application of a EGF serum for 3 months showed significant improvement on the appearance of fine lines and rhytids (wrinkles), skin texture, pore size, and various dyschromatic conditions with minimal treatment complications. The design of experiment is not the most robust (in addition to EGF serum participants were also given basic sunscreen and cleanser to use daily which could also be responsible for improvements) but definitely promising.
    In addition, a 12 week clinical trial of twice daily application of an EGF serum on 9 male and female patients yielded improvement to the appearance of atrophic acne scars (ie ice pick, boxcar, and rolling scars) and another 12 week clinical trial on 18 male and female patients who applied EGF serum below the eye twice daily resulted in milder appearance of under-eye bags.
  • FGF (FIBROBLAST GROWTH FACTOR): rh-Polypeptide-11 
    There is significantly less research on how the topical application of FGF affects skin. In the body, FGFs are regulators of cell proliferation, differentiation, and function and are involved in wound healing, embryonic development, and various other processes such as stimulating fibroblasts in skin to proliferate and manufacture more matrix (hyaluronic acid, collagen, elastin).An in vitro study involving rFGF-1 showed rFGF-1 encapsulated in lipid spheres reduced the volume and depth of wrinkles. Furthermore, a study on 2005 individuals in which platelet-rich plasma with basic Fibroblast Growth Factor (bFGF) was injected into wrinkle-prone areas of skin (ie nasolabial folds, marionette lines, nasojugal grooves, etc) resulted in an improvement to the appearance of wrinkles and depressed areas of skin. The FGF ampoule does not contain rFGF-1 nor bFGF, which are the subject of the studies mentioned, but they are of the same growth factor family.

Full Ingredients
EGF Ampoule: rh-Oligopeptide-1, Tocopherol, Allantoin, Carbomer, Arginine, Olibanum, and Rosa Damascena Flower Oil.
FGF Ampoule: rh-Polypeptide-11, Tocopherol, Carbomer, Arginine, Olibanum, and Rosa Damascena Flower Oil

Cosdna identifies carbomer (1) as a potential irritant in the EGF serum and tocopherol (2) as an acne trigger and tocopherol (2) and carbomer (1) in the FGF serum.

EGF ampoule on the left, FGF on the right


Used together, these ampoules work like a sensitive-skin friendly AHA. My skin is brighter, has noticeably less dullness, and is smoother. These are all things that AHAs do for my skin. However, whereas AHAs create a lot of inflammation and irritation for me, these ampoules don’t at all. The trade off for gentleness seems to be speed – AHAs work a lot faster, especially in terms of the brightening effect, whereas the effects of the ampoules are much more cumulative and required consistent use for 2-3 weeks to really become noticeable. If you have sensitive skin or skin that responds better to a slow and steady type of treatment, this is an awesome alternative to exfoliants to getting smoother skin.

Also worth mentioning is out of desperation, I also used a tiny amount of the EGF serum on the half dozen mosquito bites I got from my trip to Italy. Mosquitoes rarely bite me but when they do, I respond terribly. The bites swell enormously, turn red then bright purple, and itch terribly. The day after I first applied the EGF ampoule, the three worst bites de-puffed by a good 60-70% overnight and the itchiness disappeared after two days of use. I can’t say with 100% certainty the ampoule was responsible – it could have been the change in environment, climate, diet, a million other factors – but compared to tiger balm and hydrocortisone, which I had been previously using on the bites, the EGF serum brought the fastest and most dramatic relief!

I wish I had tried these ampoules when I was still struggling with acne because I would be very curious how they impact the healing process, especially with regard to speed, hyperpigmentation, and scarring. Overall, I’m impressed with the effects and think Swanicoco did the smart thing by putting these potent healing ingredients in a non-irritating, fragrance-free, bare-bones formulation. I just wish these ampoules weren’t so tiny any expensive!

Overall Score: 3.7/5


2 thoughts on “Swanicoco EGF and FGF Pure Ampoule Review

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