Neogen Dermatology Dual Layer Ceramide Oil Review

I feel like this is THE product for people who think they’re missing out. For example, if you’ve heard about the wonders of horse oil but can’t get over the idea of dead horses, this is a decent, vegan (there’s no horse, but there is snail) alternative. If you find the texture of lotion or cream to be gross but have dry skin, this is definitely the moisturizer for you. If you want to start exploring the world of face oils but find the idea of putting oil on your face confusing / scary / grease-ifying, this is a great, grease-free oil product. Lastly, if you feel like you can’t keep up with all of the cool, exotic ingredients that the Korean-Beauty-Gods keep sticking in skincare products, this is a one-stop-shop to get a lot of those ingredients in your routine. Intrigued yet? You should be because I absolutely LOVE this product!

Packaging + Appearance

This is a cool looking oil that consists of two distinct layers. The top layer is “essence,” which consists of the many many extracts and miscellaneous active ingredients, and the bottom layer is a blend of oils. To use, you take the bottle, shake vigorously for a few seconds so the two layers combine, and then use the dropper top to extract the oil for use.

neogen dual layer ceramide oil

The two layers actually mix very easily. In fact, it took 2 days after I received this in the mail for the layers to separate enough for me to take this picture.


After the layers are mixed together, they form a watery but milky colored liquid that I will be referring to as an essence-oil, or EO for short. This liquid is very fluid, has great slip, and sinks into my skin really quickly. Even though the EO comprises a significant amount of oil, it is more similar in texture to an emulsion than an oil and happily avoids common complications that a face oil might pose, such as leaving behind a visible, oily layer.

neogen dermatology dual layer ceramide oil

To use, I load up the dropper cap, squeeze the EO onto my hands, rub my hands together to warm up the EO, then pat all over my face. At first, I was careful to only use the suggested 4 drops, but quickly learned that I can use A LOT more than that and it will still sink into my skin cleanly. The EO has a dewy but not greasy finish. If you’re ok with the amount of dewiness you get from an Iope bb cushion, you shouldn’t have any issues with this oil. 

neogen dermatology swatch

I have been using this EO in place of a moisturizing cream and I love it! It is easier to apply than a cream, effectively seals in moisture, and absorbs into my skin better. In fact, the way that this essence-oil sinks into my skin is reminds me of how horse oil products seem to melt into my skin, and I love me some horse oil


This oil gets a whole section for ingredients because it contains everything. Seriously, it’s pretty wild. This is what the list looks like, in its entirety:

water, butylene glycol, canola oil, cetearyl ethylhexanoate, glycerin, niacinamide, 1,2-hexanediol, octyldodecanol, caprylic / capric triglycerides, ceramide 3, hydrogenated lecithin, simmondsia chinensis (jojoba) seed oil, moringa oleifera seed oil, camellia sinensis seed oil, honey extract, butyrospermum parkii (shea) butter extract, adansonia digitata leaf extract, persea gratissima (avocado) fruit extract, trehalose, human oligopeptide-1, hydrolyzed collagen, acetyl glucosamine, brassica campestris (rapeseed) oil, linum usitatissimum (linseed) seed oil, juglans regia (walnut) seed oil, vitis vinifera (grape) seed oil, glycine soja (soybean) oil, argania spinosa kernel oil, propolis extract, magnesium ascorbyl phosphate, retinyl palmitate, snail secretion filtrate, allium sativum (garlic) bulb extract, euterpe oleracea fruit extract, morus alba fruit extract, rubus coreanus fruit extract, sambucus nigra fruit extract, black sugar extract, theobroma cacao (cocoa) extract, charcoal powder, solanum melongena (eggplant) fruit extract, sepia, porphyra tenera extract, polygonum fagopyrum (buckweed seed) extract, vitis vinifera (grape) fruit extract, coffea arabica fruit extract, inonotus obliquus (mushroom) extract, cassia obtusifolia seed extract, corthellus shiitake (mushroom) extract, mirabilis jalapa seed extract, piper nigrum (pepper) seed extract, fagus sylvatica seed extract, aronia melanocarpa fruit extract, dictyopteris membranacea extract, rose extract, cinnamomum cassia bark extract, anona cherimolia fruit extract, rhus semialata gall extract, prunus mume fruit extract, cellulose gum, adenosine, bifida ferment lysate, artemisia annua extract, calendula officinalis flower extract, symphytum officinale leaf extract, helichrysum italicum (everlasting) extract, azadirachta indica leaf extract, zanthoxylum piperitum fruit extract, pulsatilla koreana extract, usnea barbata (lichen) extract, melissa offinalis flower/leaf/stem water, chamomilla recutita (matricaria) flower water, calenula officinalis flower water, rosa damascena flower water, triticum spelta seed water, melaleuca alternifolia (tea tree) leaf extract, cetearyl alcohol, hydrogenated vegetable oil, behenyl alcohol, stearic acid, polyglyceryl-3 methylglucose distearate, glyceryl stearate SE, methyl glucose sesquistearate, dimethicone, disodium EDTA, phenoxyethanol, ethylhexylglycerin, safflower yellow, gardenia red, fragrance

To make this easier to read, I’ve broken the ingredients into a few different categories: oils, extracts, miscellaneous interesting ingredients, and other.

neogen dermatology

The bad thing about having a product with a huge list of extracts is that the amount of each extract is necessarily tiny. If you’re specifically interested in adding a Vitamin C product to your skincare routine, this is not going to suffice, even though it contains magnesium ascorbyl phosphate, a Vitamin C derivative. The good thing about having a product with a huge list of extracts and ingredients is that collectively, something is probably happening. Some skincare experts think that with antioxidants, for example, more is better. 

A potential risk in using a product with so many ingredients is that if you have sensitive or acne prone skin, one or more of the extracts may trigger acne. The acne triggers that cosdna analysis flags are butylene glycol (1), jojoba oil (2), soybean oil (3), retinyl palmitate (2), cetearyl alcohol (2), hydrogenated vegetable oil (3), stearic acid (2), glyceryl stearate SE (3), and dimethicone (1). Personally, cosdna ratings have never been a great predicator for what will and will not trigger acne for me (which is one of the reasons I’ve started to move away from using cosdna analysis in my reviews). For example, my skin is bulletproof against highly comedogenic oils such as coconut oil and cocoa butter (both rated 4), but will break out badly to papain, which cosdna does not even flag as an acne trigger. For what it’s worth, but I have not had any issues with acne or irritation with this product.

The Takeaway

This product has an overachieving ingredient list, absorbs beautifully into my skin, and does a fantastic job keeping my skin hydrated. Highly recommend to anyone unless you have very acne-prone skin, in which case the ingredient list can prove to be problematic.

I bought this from ebay on a whim for $24. It’s also available on Koreadepart for a few dollars more.

Neogen oil

Disclosure: Product paid for by me. Affiliate links. See my full disclosure policy here.

26 thoughts on “Neogen Dermatology Dual Layer Ceramide Oil Review

  1. Angela and Renee says:

    I lemmed this so hard after reading about it on your blog because I love facial oils and I’ve been wanting to incorporate ceramides. Almost pulled the trigger but then I noticed it has snail secretion filtrate. 🙀 So not *quite* vegan (many vegans would count snail products, just as they do bee products, as animal ingredients). It actually annoys me because the amount is probably minute and unnecessary in the grand scheme of things. I shall just watch you glow from afar 😊 –Angela

    Liked by 1 person

    • V. Rex says:

      Oh, I didn’t even think of that! I went through a hefty vegan-ish phase (I made a few exceptions, like processed sugar because sugar) a few years back too. -_- It’s been corrected in the review! Do you only use vegan products?


      • Angela and Renee says:

        I try to but admit I’ve made exceptions (usually for Dior and Chanel lipsticks 👀). I’m pretty good at avoiding animals ingredients in skincare though–meaning I’ve missed out on snails, starfish, donkey, … Good thing there’s enough variety that I’m never short on things to buy 😹

        Liked by 1 person

  2. The Acid Queen says:

    Oh man, this stuff sounds amazing! I want to love most facial oils a lot more than I actually do – the feel of oil sitting on my skin is just nails on a chalkboard to me – so this sounds like a perfect middle ground between essence and oil. Thanks for the review!


  3. ninianaw says:

    I use it as a final moisturing step or with my mizon recovery gel cream and hadalabo lotion I really like it my skin is less red and flaky it makes a big difference for me


  4. mashimaroluff says:

    Omg this sound like a god-send. I am the person who have the exact problems u listed. But the ingredients does make me wary. How would u compare this to the goodal waterway water oil though? They seem to be very similar products

    Liked by 1 person

    • V. Rex says:

      There are a whole lot of ingredients, huh? Compared to the water oil, this cera-oil is a bit denser and less slippery. I really like both but they do serve a similar function. I find this oil easier to layer into my routine (it sinks into my skin a little easier) so I find myself reaching for this more.


  5. Estella says:

    Do you know where the hydrolyzed collagen included comes from? If it is animal sourced then it wouldn’t be vegan. It sounds really nice but that potentiality deters me.

    Liked by 1 person

      • Estella says:

        Yes I agree that it is in some cases, but some vegans still eat honey, so it’s a bit of a grey area imo. I definitely don’t want to use animal skin in my products though.

        Liked by 1 person

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